What is Crohn's Disease

Crohn’s disease (CD) is named after the doctor who first described it in 1932. (Since he did not have the disease itself, it is sometimes more accurately called Crohn disease).

Unlike Ulcerative Colitis which is predominantly located in or around the large bowel, The inflammation from Crohn’s disease can strike anywhere in the gastrointestinal (GI) tract, from mouth to anus, but is usually located in the lower part of the small bowel and the upper end of the colon. Patches of inflammation are interspersed between healthy portions of the gut and can penetrate the intestinal layers from inner to outer lining.

CD can also affect the mesentery, which is the network of tissue that holds the small bowel to the abdomen and contains the main intestinal blood vessels and lymph glands.

Location effected by Crohn's
What are the Symptoms of Crohn’s Disease?

Since CD can be located anywhere in the GI tract, symptoms can vary. On the whole, however, they often include abdominal pain, cramping, diarrhoea, nausea, vomiting and not surprisingly, weight loss and lack of energy.

Crohn’s disease is a chronic (lifelong) illness. People who have CD will experience periods of acute flare-ups, when their symptoms are active and other times when their symptoms go into remission. The average risk of a flare-up in any one year is approximately 30%.

In 25% of those with CD, perianal disease may also develop. “Peri” means “around” – therefore perianal disease is located “around the anus”.

Specifically, this means that a person could develop:

  • painful, swollen skin tags (that appear to be haemhorrhoids but are not)
  • abscesses (bags of pus created inside the body as a result of infection)
  • fistulas (infections that have tunnelled from the abscess to a hollow organ such as the rectum or vagina)

Many of the Crohn’s sufferers also experience “extra-intestinal manifestations” or conditions that affect areas outside of the intestines. For more information on the extra-intestinal manifestations of Crohn’s disease continue reading here.

Can Crohn’s Disease be cured?

There is no cure for Crohn’s disease – yet.

Please Note
This educational content was originally published by The Crohn’s and Colitis Foundation of Canada (CCFC) is a national not-for-profit voluntary medical research Foundation. Its mission is to find the cure for inflammatory bowel disease.  Please join with us in our mission to “Find the Cure” by clicking on our online donations and giving what you can.